Growing global tech businesses
out of Bristol

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Helping you make your impact in the world

Our support is designed for you. If you join us, you’ll enjoy tailored support crafted around your ambitions and introductions to an amazing network of companies and advisers.

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Your success is our success

We’ve helped over 450 companies, in 20+ sectors, raise over £742 million in investment.

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Jack Fertility logo, black text with black swirl graphic

Lily and Nick at Jack Fertility - changing the game in male fertility testing

"SETsquared Bristol has played a key role in turning our idea into reality. The expert advice, practical workshops, personalised coaching and support has helped us to sharpen our business strategy, prepare for funding, and grow our reach."

Jack Fertility logo, black text with black swirl graphic

Andrew at Fathom - global leader in flood and climate risk

"SETsquared Bristol was invaluable in educating the founding team in how to structure and build a company. The mentoring was also very useful, and we made some great connections at events."

Ferryx logo, blue and oragne text with circles

Jenny at Ferryx - innovative biotech solutions to common gut problems

"SETsquared Bristol is helping me to learn and grow my business skills, constantly challenging me and keeping me on track, all within a thriving, supportive community of like-minded individuals."

Ferryx logo, blue and oragne text with circles

Neciah at FluoretiQ - revolutionising bacterial diagnostics

“It’s incredibly useful to meet entrepreneurs with similar challenges to share solutions. We have a much wider network through SETsquared, ensuring our developments can be heard by those who need to hear them ...”

Fast track your tech business

Hear from our companies on how SETsquared Bristol has helped them grow their businesses.

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Featured news and insights

RtoR group shot

From research to real world impact: why the First Pitch Showcase matters

6th May 2026
The upcoming First Pitch Showcase marks a significant moment for the University of Bristol’s Research to Reward programme. It brings together pioneering research, entrepreneurship, and a growing commitment to turning...
Ferryx exhibiting at Investment Futures event 2024

The Science Isn’t the Selling Point: Lessons from Founders

7th April 2026
She spent nearly a decade on the science. Identified something that worked when nothing else did. Tested it. Patented it. Then she waited and nobody called. That was one of...
Tech-xpo 2021

SETsquared Announces Move to Temple Quarter Enterprise Campus

31st March 2026
Engine Shed will close in December this year, marking the end of 13 impactful years supporting Bristol’s innovation community. SETsquared Bristol will continue its work uninterrupted, relocating to the University...
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